Publications in recent years

Publication in last 5 years. For full list of publications please look at: https://scholar.google.co.il/citations?user=6xsqzioAAAAJ&hl=iw&oi=ao.

2021

Insular cortex neurons encode and retrieve specific immune responses. Tamar Koren, Re’ee Yifa, Mariam Amer, Maria Krot, Nadia Boshnak ,Tamar L. Ben-Shaanan, Hilla Azulay-Debby, Itay Zalayat, Eden Avishai, Haitham Hajjo, Maya Schiller, Hedva Haykin Ben Korin, Dorit Farfara, Fahed Hakim, Oren Kobiler, Kobi Rosenblum, Asya Rolls.  Published: November 08, 2021DOI:https://doi.org/10.1016/j.cell.2021.10.013

The Role of the Eukaryotic Elongation Factor 2 (eEF2) Pathway in Neuronal Function.  Elham Taha and Kobi Rosenblum. The Oxford Handbook of Neuronal Protein Synthesis. Edited by Wayne S. Sossin. Print Publication Date: Jun 2021 Subject: Neuroscience, Molecular and Cellular Systems DOI: 10.1093/oxfordhb/9780190686307.013.4

Somatostatin Interneurons of the Insula Mediate QR2 Dependent Novel Taste Memory Enhancement. Gould NL, Kolatt Chandran S, Kayyal H, Edry E, Rosenblum K. eNeuro. 2021 Sep 13:ENEURO.0152-21.2021. doi: 10.1523/ENEURO.0152-21.2021. Online ahead of print.PMID: 34518366

Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice. Kayyal H, Chandran SK, Yiannakas A, Gould N, Khamaisy M, Rosenblum K. Elife. 2021 Jul 5;10:e66686. doi:10.7554/eLife.66686.PMID: 34219650

Parvalbumin interneuron inhibition onto anterior insula neurons projecting to the basolateral amygdala drives aversive taste memory retrieval. Yiannakas A, Kolatt Chandran S, Kayyal H, Gould N, Khamaisy M, Rosenblum K.Curr Biol. 2021 Apr 23:S0960-9822(21)00523-6. doi: 10.1016/j.cub.2021.04.010. Online ahead of print.PMID: 33930301

4E-BP2–dependent translation in parvalbumin neurons controls epileptic seizure threshold. Vijendra Sharma, Rapita Sood,   Danning Lou, Tzu-Yu Hung, Maxime Lévesque,   Yelin Han,  Jeremy Y. Levett, Peng Wang,  Shravan Murthy, Shannon Tansley, Siyan Wang, Nadeem Siddiqui,  Soroush Tahmasebi, Kobi Rosenblum, Massimo Avoli, Jean-Claude Lacaille,  Nahum Sonenberg, and Arkady Khoutorsky PNAS April 13, 2021 118 (15) e2025522118; https://doi.org/10.1073/pnas.2025522118

2020

Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation. Gould NL, Sharma V, Hleihil M, Kolatt Chandran S, David O, Edry E, Rosenblum K. J Neurosci. 2020 Oct 12:JN-RM-1243-20. doi: 10.1523/JNEUROSCI.1243-20.2020

eIF2α controls memory consolidation via excitatory and somatostatin neurons. Vijendra Sharma , Rapita Sood , Abdessattar Khlaifia , Mohammad Javad Eslamizade , Tzu-Yu Hung , Danning Lou , Azam Asgarihafshejani , Maya Lalzar , Stephen J Kiniry , Matthew P Stokes , Noah Cohen , Alissa J Nelson , Kathryn Abell , Anthony P Possemato , Shunit Gal-Ben-Ari , Vinh T Truong , Peng Wang , Adonis Yiannakas , Fatemeh Saffarzadeh , A Claudio Cuello , Karim Nader , Randal J Kaufman , Mauro Costa-Mattioli , Pavel V Baranov , Albert Quintana , Elisenda Sanz , Arkady Khoutorsky , Jean-Claude Lacaille , Kobi Rosenblum , Nahum Sonenberg .Nature 2020 Oct;586(7829):412-416. doi: 10.1038/s41586-020-2805-8. Epub 2020 Oct 7

eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition. Elham Taha , Sudarshan Patil , Iliana Barrera , Julia Panov , Mohammad Khamaisy , Christopher G Proud, Clive R Bramham , Kobi Rosenblum. Curr Biol 2020 Jul 15;S0960-9822(20)30913-1. doi: 10.1016/j.cub.2020.06.061

D1 Dopamine Receptor Activation Induces Neuronal eEF2 Pathway-Dependent Protein synthesis. Orit David, Iliana Barrera, Nathaniel Gould, Shunit Gal-Ben-Ari and Kobi Rosenblum. Front. Mol. Neurosci.15 May 2020

Muscarinic-Dependent miR-182 and QR2 Expression Regulation in the Anterior Insula Enables Novel Taste Learning. Gould NL, Elkobi A, Edry E, Daume J, Rosenblum K.eNeuro. 2020 Mar 20. pii: ENEURO.0067-20.2020.

Measuring mRNA translation in neuronal processes and somata by tRNA-FRET. Koltun B, Ironi S, Gershoni-Emek N, Barrera I, Hleihil M, Nanguneri S, Sasmal R, Agasti SS, Nair D, Rosenblum K. Nucleic Acids Res 6;48(6):e32. 2020 Apr doi:10.1093/nar/gkaa042

2019

PKR: A Kinase to Remember. Shunit Gal-Ben-Ari, Iliana Barrera , Marcelo Ehrlich , Kobi Rosenblum Front Mol Neurosci. 2019 Jan 9;11:480.doi: 10.3389/fnmol.2018.00480. eCollection 2019.

Multi-input Synapses, but Not LTP-Strengthened Synapses, Correlate With Hippocampal Memory Storage in Aged Mice. Wajeeha Aziz  Igor Kraev , Keiko Mizuno , Alastair Kirby , Ton Fang , Huzefa Rupawala , Kamillia Kasbi , Stephanie Rothe , Felix Jozsa , Kobi Rosenblum , Michael G Stewart , K Peter Giese  Curr Biol 2019 Nov 4;29(21):3600-3610.e4. doi: 10.1016/j.cub.2019.08.064. Epub Oct 17,2019.

Activity of Insula to Basolateral Amygdala Projecting Neurons is Necessary and Sufficient for Taste Valence Representation. Haneen Kayyal, Adonis Yiannakas, Sailendrakumar Kolatt Chandran, Mohammad Khamaisy, Vijendra Sharma, and Kobi Rosenblum. J Neurosci. 2019 Nov20:39(47):9369-9382).

2018

Acquired taste valence encoding in cortico-amygdala circuits. Lavi K, Jacobson GA, Rosenblum K, Lüthi A. Cell Reports. 24(2):278-283. doi: 10.1016/j.celrep.2018.06.053, 2018

Calcium-Calmodulin-Dependent Kinase II and Eukaryotic Elongation Factor-2 Kinase Pathways Mediate the Antidepressant Action of Ketamine. Adaikkan C, Taha E, Barrera I, David O, Rosenblum K. Biol Psych. pii: S0006-3223(17)32247-3. doi: 10.1016/j.biopsych.2017.11.028. 2018

2017

Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties. Sharma V, Ounallah-Saad H, Chakraborty D, Hleihil M, Sood R, Barrera I, Edry E, Kolatt Chandran S, Tabou de Leon SB, Kaphzan H, Rosenblum K. J Neurosci. pii: 0628-17. doi: 10.1523/JNEUROSCI.0628-17,2017.

The Insula and Taste Learning. Yiannakas A, Rosenblum K. Front Mol Neurosci. 10:335. doi: 10.3389/fnmol.2017.00335. eCollection Review, 2017.